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Reovirus May be a Novel Approach to Prostate Cancer Treatment
1)Therapeutic activity demonstrated in vitro and in vivo; 2) Virus' effect is selective for prostate cancer; not normal tissue; 3) Safety and efficacy shown in early-stage prostate cancer.
Effective prostate cancer treatment discovery
(Monash University) Monash University biomedical scientists have identified a new way to treat castrate resistant cells in prostate cancer sufferers -- the most common cancer in Australian men.
Do men with early prostate cancer commit suicide more frequently?
(European Association of Urology) The risk of suicide is increased among cancer patients including men with PCa. To assess the risk of suicide among men diagnosed with PCa subsequent to PSA testing, a nation-wide study was carried out in Sweden. The results are published in the March issue of European Urology, the scientific journal of the European Association of Urology.
What it might take to unravel the 'lean mean machine' that is cancer
(Research Australia) Scientists from Sydney's Garvan Institute of Medical Research have published a paper, online today in Nature Cell Biology, describing gene expression in a prostate cancer cell: more sweeping, more targeted and more complex than we could ever have imagined, even five years ago.The study shows that changes within the prostate cancer cell "epigenome" (biochemical processes that target DNA and affect gene expression) alter the expression of many genes, silencing their expression within large regions of DNA -- nearly 3 percent of the cell's genome.
Small liquid sensor may detect cancer instantly, could lead to home detection kit
(University of Missouri-Columbia) What if it were possible to go to the store and buy a kit to quickly and accurately diagnose cancer, similar to a pregnancy test? A University of Missouri researcher is developing a tiny sensor, known as an acoustic resonant sensor, that is smaller than a human hair and could test bodily fluids for a variety of diseases, including breast and prostate cancers.
Lower detection of prostate cancer with PSA screening in US than in a European randomized trial
(Journal of the National Cancer Institute) Fewer prostate cancers were detected by prostate-specific antigen (PSA) screening in the US than in a European randomized trial because of lower screening sensitivity, according to a new brief communication published online February 8 in the Journal of the National Cancer Institute.
Loss of gene function makes prostate cancer cells more aggressive
(UT Southwestern Medical Center) Prostate cancer cells are more likely to spread to other parts of the body if a specific gene quits functioning normally, according to new data from researchers at UT Southwestern Medical Center.
Immediate risk of suicide and cardiovascular death after a prostate cancer diagnosis
(Journal of the National Cancer Institute) Being diagnosed with prostate cancer may increase a man's risk of suicide or cardiovascular death, especially right after diagnosis, according to a new study published online Feb. 2 in the Journal of the National Cancer Institute.
Biochemical profile may help diagnose, determine aggressiveness of prostate cancer
Magnetic resonance spectroscopy -- which analyzes the biochemistry rather than the structure of tissues -- may someday be able both to pinpoint the precise location of prostate cancer and to determine the tumor's aggressiveness, information that could help guide treatment planning. Researchers report how spectroscopic analysis of the biochemical makeup of prostate glands accurately identified the location of tissue confirmed to be malignant by conventional pathology.
Starting penile rehabilitation early improves erectile function recovery after RP
Men who delay the start of penile rehabilitation after radical prostatectomy for prostate cancer do not recover erectile function as well as men who begin rehabilitation immediately, report US researchers. (Source: MedWire News - Oncology)
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